Acura MDX vs Lexus RX350L
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2022 Lexus RX350L
Overview
| Spec | Acura MDXMDX SUV | Lexus RX350L350L |
|---|---|---|
| Selected trim | MDX SUV | 350L |
| Body style | SUV | SUV |
| Drivetrain | front wheel drive | front wheel drive |
| Fuel type | premium unleaded (recommended) | premium unleaded (recommended) |
| Transmission | 10-speed shiftable automatic | 8-speed shiftable automatic |
| Engine type | gas | gas |
| Model year | 2026 | 2022 |
Pricing & market
| Spec | Acura MDXMDX SUV | Lexus RX350L350L |
|---|---|---|
| MSRP | $51,800 | $48,750 (best) |
| Lowest listing price | $8,654 (best) | — |
| Median listing price | $60,138 (best) | — |
| Highest listing price | $79,593 (best) | — |
| For sale now | 121 (best) | 0 |
Fuel economy & range
| Spec | Acura MDXMDX SUV | Lexus RX350L350L |
|---|---|---|
| Combined MPG | 22 MPG | 22 MPG |
| City MPG | 19 MPG | 19 MPG |
| Highway MPG | 26 MPG | 26 MPG |
| Fuel tank | 18.5 gal | 19.2 gal (best) |
Performance
| Spec | Acura MDXMDX SUV | Lexus RX350L350L |
|---|---|---|
| Horsepower | 290 hp | 290 hp |
| Torque | 267 lb-ft (best) | 263 lb-ft |
| Engine size | 3.5 L | 3.5 L |
| Cylinders | V6 | V6 |
Size & capability
| Spec | Acura MDXMDX SUV | Lexus RX350L350L |
|---|---|---|
| Seating | 7 seats | 7 seats |
| Doors | 4 | 5 (best) |
| Cargo volume | 95 cu ft (best) | 58.5 cu ft |
| Towing capacity | 3,500 lbs | 3,500 lbs |
| Payload | — | 1,433 lbs (best) |
| Curb weight | 4,268 lbs (best) | 4,464 lbs |
| Ground clearance | 7.3 in | 8.1 in (best) |
| Wheelbase | 113.8 in (best) | 109.8 in |
| Length | 198.4 in (best) | 196.9 in |
| Width | 78.7 in (best) | 74.6 in |
| Height | 67.9 in (best) | 67.3 in |
Safety & recalls
| Spec | Acura MDXMDX SUV | Lexus RX350L350L |
|---|---|---|
| NHTSA overall | Not Rated | — |
| Frontal crash (driver) | 4 / 5 ★ (best) | — |
| Frontal crash (passenger) | 4 / 5 ★ (best) | — |
| Side crash (driver) | 5 / 5 ★ (best) | — |
| Side crash (passenger) | 5 / 5 ★ (best) | — |
| Side pole | 5 / 5 ★ (best) | — |
| Rollover | Not Rated | — |
| Open recalls (YMM scope) | 1 | None reported (best) |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Acura MDX | Lexus RX350L |
|---|---|---|
| 1 | MDX SUV $51,800 MSRP(Currently comparing) | 350L $48,750 MSRP(Currently comparing) |
| 2 | MDX SUV $57,200 MSRP | 350L $50,150 MSRP |
| 3 | MDX SUV $54,000 MSRP | 350L Luxury $54,750 MSRP |
| 4 | MDX SUV $59,400 MSRP | 350L Luxury $56,150 MSRP |
| 5 | MDX SUV $62,400 MSRP | — |
| 6 | MDX SUV $66,900 MSRP | — |
| 7 | MDX SUV $68,900 MSRP | — |
| 8 | Type S $75,850 MSRP | — |
Live inventory
Acura MDX121 for sale
See all
Used2020 Acura MDX
Technology
Platinum White Pearl•Ebony132,889 mi$20,890Drive Appeal
Eden Prairie, MN
Used2024 Acura MDX
SH-AWD w/Tech
Lunar Silver Metallic•Ebony23,315 mi$41,990Classic Volkswagen Gastonia
Gastonia, NC
Used2019 Acura MDX
Automatic
Canyon Bronze Metallic38,477 mi$28,535Velocity Autohaus
Hasbrouck Heights, NJ
Used2022 Acura MDX
Technology
Liquid Carbon Metallic•Ebony109,131 mi$28,431Fred Anderson Toyota of Charleston
Charleston, SC
Certified2022 Acura MDX
Technology
Liquid Carbon Metallic•Ebony100,126 mi$28,258Stokes Hodges Ford Graniteville
Graniteville, SC
Certified2024 Acura MDX
3.5L
Platinum White Pearl•Ebony15,838 mi$38,500Plaza Auto Mall
Brooklyn, NY
Acura MDX vs Lexus RX350L FAQ
- Which is better: 2026 Acura MDX or 2022 Lexus RX350L?
- It depends on priorities. OpenDealer compares 2026 Acura MDX vs 2022 Lexus RX350L on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Acura MDX or 2022 Lexus RX350L?
- Based on starting MSRP, the 2022 Lexus RX350L starts lower at $48,750. Live Acura MDX listings start at $8,654.
- Which has better startingMsrp: 2026 Acura MDX or 2022 Lexus RX350L?
- The 2022 Lexus RX350L leads on startingMsrp in this comparison (48,750).
- Which has better horsepower: 2026 Acura MDX or 2022 Lexus RX350L?
- The 2026 Acura MDX leads on horsepower in this comparison (355).
- Which has better maxTowingLbs: 2026 Acura MDX or 2022 Lexus RX350L?
- The 2026 Acura MDX leads on maxTowingLbs in this comparison (5,000).
- How do the NHTSA safety ratings compare for 2026 Acura MDX vs 2022 Lexus RX350L?
- NHTSA overall crash-test ratings in this comparison: Acura MDX (Not Rated/5 NHTSA overall).