Acura MDX vs Mercedes-Benz ML350
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2015 Mercedes-Benz ML350
Overview
| Spec | Acura MDXMDX SUV | Mercedes-Benz ML350ML 350 |
|---|---|---|
| Selected trim | MDX SUV | ML 350 |
| Body style | SUV | SUV |
| Drivetrain | front wheel drive | rear wheel drive |
| Fuel type | premium unleaded (recommended) | premium unleaded (required) |
| Transmission | 10-speed shiftable automatic | 7-speed shiftable automatic |
| Engine type | gas | gas |
| Model year | 2026 | 2015 |
Pricing & market
| Spec | Acura MDXMDX SUV | Mercedes-Benz ML350ML 350 |
|---|---|---|
| MSRP | $51,800 | $48,300 (best) |
| Lowest listing price | $8,654 (best) | — |
| Median listing price | $60,343 (best) | — |
| Highest listing price | $79,593 (best) | — |
| For sale now | 135 (best) | 0 |
Fuel economy & range
| Spec | Acura MDXMDX SUV | Mercedes-Benz ML350ML 350 |
|---|---|---|
| Combined MPG | 22 MPG (best) | 20 MPG |
| City MPG | 19 MPG (best) | 18 MPG |
| Highway MPG | 26 MPG (best) | 24 MPG |
| Fuel tank | 18.5 gal | 24.6 gal (best) |
Performance
| Spec | Acura MDXMDX SUV | Mercedes-Benz ML350ML 350 |
|---|---|---|
| Horsepower | 290 hp | 302 hp (best) |
| Torque | 267 lb-ft | 273 lb-ft (best) |
| Engine size | 3.5 L | 3.5 L |
| Cylinders | V6 | V6 |
Size & capability
| Spec | Acura MDXMDX SUV | Mercedes-Benz ML350ML 350 |
|---|---|---|
| Seating | 7 seats (best) | 5 seats |
| Doors | 4 | 5 (best) |
| Cargo volume | 95 cu ft (best) | 80.3 cu ft |
| Towing capacity | 3,500 lbs (best) | — |
| Curb weight | 4,268 lbs (best) | — |
| Ground clearance | 7.3 in (best) | — |
| Wheelbase | 113.8 in | 114.8 in (best) |
| Length | 198.4 in (best) | 189.1 in |
| Width | 78.7 in | 84.3 in (best) |
| Height | 67.9 in | 70.7 in (best) |
Safety & recalls
| Spec | Acura MDXMDX SUV | Mercedes-Benz ML350ML 350 |
|---|---|---|
| NHTSA overall | Not Rated | — |
| Frontal crash (driver) | 4 / 5 ★ (best) | — |
| Frontal crash (passenger) | 4 / 5 ★ (best) | — |
| Side crash (driver) | 5 / 5 ★ (best) | — |
| Side crash (passenger) | 5 / 5 ★ (best) | — |
| Side pole | 5 / 5 ★ (best) | — |
| Rollover | Not Rated | — |
| Open recalls (YMM scope) | 1 (best) | 5 |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Acura MDX | Mercedes-Benz ML350 |
|---|---|---|
| 1 | MDX SUV $51,800 MSRP(Currently comparing) | ML 350 $48,300 MSRP(Currently comparing) |
| 2 | MDX SUV $57,200 MSRP | ML 350 4MATIC $50,800 MSRP |
| 3 | MDX SUV $54,000 MSRP | — |
| 4 | MDX SUV $59,400 MSRP | — |
| 5 | MDX SUV $62,400 MSRP | — |
| 6 | MDX SUV $66,900 MSRP | — |
| 7 | MDX SUV $68,900 MSRP | — |
| 8 | Type S $75,850 MSRP | — |
Live inventory
Acura MDX135 for sale
See all
Used2020 Acura MDX
Technology
Platinum White Pearl•Ebony132,889 mi$20,890Drive Appeal
Eden Prairie, MN
Used2024 Acura MDX
SH-AWD w/Tech
Lunar Silver Metallic•Ebony23,315 mi$41,990Classic Volkswagen Gastonia
Gastonia, NC
Used2019 Acura MDX
Automatic
Canyon Bronze Metallic38,477 mi$28,535Velocity Autohaus
Hasbrouck Heights, NJ
Used2023 Acura MDX
Type S w/Advance Package
Lunar Silver Metallic•Azurite Blue76,313 mi$39,997Genesis of Cherry Hill
Marlton, NJ
Used2022 Acura MDX
Technology
Liquid Carbon Metallic•Ebony109,131 mi$28,431Fred Anderson Toyota of Charleston
Charleston, SC
Certified2022 Acura MDX
Technology
Liquid Carbon Metallic•Ebony100,126 mi$28,258Stokes Hodges Ford Graniteville
Graniteville, SC
Acura MDX vs Mercedes-Benz ML350 FAQ
- Which is better: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- It depends on priorities. OpenDealer compares 2026 Acura MDX vs 2015 Mercedes-Benz ML350 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- Based on starting MSRP, the 2015 Mercedes-Benz ML350 starts lower at $48,300. Live Acura MDX listings start at $8,654.
- Which has better startingMsrp: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- The 2015 Mercedes-Benz ML350 leads on startingMsrp in this comparison (48,300).
- Which has better combinedMpg: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- The 2026 Acura MDX leads on combinedMpg in this comparison (22).
- Which has better horsepower: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- The 2026 Acura MDX leads on horsepower in this comparison (355).
- Which has better seats: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- The 2026 Acura MDX leads on seats in this comparison (7).
- Which has better maxTowingLbs: 2026 Acura MDX or 2015 Mercedes-Benz ML350?
- The 2026 Acura MDX leads on maxTowingLbs in this comparison (5,000).
- How do the NHTSA safety ratings compare for 2026 Acura MDX vs 2015 Mercedes-Benz ML350?
- NHTSA overall crash-test ratings in this comparison: Acura MDX (Not Rated/5 NHTSA overall).