Audi A4 Quattro vs Lexus IS350
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2026 Lexus IS350
Overview
| Spec | Audi A4 QuattroPremium S line | Lexus IS350350 F SPORT Design |
|---|---|---|
| Selected trim | Premium S line | 350 F SPORT Design |
| Body style | Sedan | Sedan |
| Drivetrain | all wheel drive | rear wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | 7-speed automated manual | 8-speed shiftable automatic |
| Engine type | mild hybrid | gas |
| Model year | 2025 | 2026 |
Pricing & market
| Spec | Audi A4 QuattroPremium S line | Lexus IS350350 F SPORT Design |
|---|---|---|
| MSRP | $44,100 (best) | $45,500 |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Audi A4 QuattroPremium S line | Lexus IS350350 F SPORT Design |
|---|---|---|
| Combined MPG | 26 MPG (best) | 23 MPG |
| City MPG | 23 MPG (best) | 20 MPG |
| Highway MPG | 32 MPG (best) | 28 MPG |
| Fuel tank | 15.3 gal | 17.4 gal (best) |
Performance
| Spec | Audi A4 QuattroPremium S line | Lexus IS350350 F SPORT Design |
|---|---|---|
| Horsepower | 261 hp | 311 hp (best) |
| Torque | 273 lb-ft | 280 lb-ft (best) |
| Engine size | 2 L | 3.5 L (best) |
| Cylinders | I4 | V6 |
Size & capability
| Spec | Audi A4 QuattroPremium S line | Lexus IS350350 F SPORT Design |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Cargo volume | 12 cu ft (best) | 10.8 cu ft |
| Payload | 1,014 lbs (best) | — |
| Curb weight | 3,682 lbs (best) | 3,792 lbs |
| Wheelbase | 111 in (best) | 110.2 in |
| Length | 187.5 in (best) | 185.8 in |
| Width | 72.7 in (best) | 72.4 in |
| Height | 56.2 in | 56.5 in (best) |
Safety & recalls
| Spec | Audi A4 QuattroPremium S line | Lexus IS350350 F SPORT Design |
|---|---|---|
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Audi A4 Quattro | Lexus IS350 |
|---|---|---|
| 1 | Premium S line $44,100 MSRP(Currently comparing) | 350 F SPORT Design $45,500 MSRP(Currently comparing) |
| 2 | Premium Plus S line $48,600 MSRP | 350 F SPORT Design $47,500 MSRP |
| 3 | Prestige S line $51,300 MSRP | 350 F SPORT $47,950 MSRP |
| 4 | — | 350 F SPORT $49,950 MSRP |
Audi A4 Quattro vs Lexus IS350 FAQ
- Which is better: 2025 Audi A4 Quattro or 2026 Lexus IS350?
- It depends on priorities. OpenDealer compares 2025 Audi A4 Quattro vs 2026 Lexus IS350 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2025 Audi A4 Quattro or 2026 Lexus IS350?
- Based on starting MSRP, the 2025 Audi A4 Quattro starts lower at $44,100.
- Which has better startingMsrp: 2025 Audi A4 Quattro or 2026 Lexus IS350?
- The 2025 Audi A4 Quattro leads on startingMsrp in this comparison (44,100).
- Which has better combinedMpg: 2025 Audi A4 Quattro or 2026 Lexus IS350?
- The 2025 Audi A4 Quattro leads on combinedMpg in this comparison (26).
- Which has better horsepower: 2025 Audi A4 Quattro or 2026 Lexus IS350?
- The 2026 Lexus IS350 leads on horsepower in this comparison (311).