Cadillac CT4 vs Lexus IS350
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2026 Lexus IS350
Overview
| Spec | Cadillac CT4Luxury | Lexus IS350350 F SPORT Design |
|---|---|---|
| Selected trim | Luxury | 350 F SPORT Design |
| Body style | Sedan | Sedan |
| Drivetrain | rear wheel drive | rear wheel drive |
| Fuel type | premium unleaded (recommended) | premium unleaded (required) |
| Transmission | 8-speed shiftable automatic | 8-speed shiftable automatic |
| Engine type | gas | gas |
| Model year | 2026 | 2026 |
Pricing & market
| Spec | Cadillac CT4Luxury | Lexus IS350350 F SPORT Design |
|---|---|---|
| MSRP | $35,600 (best) | $45,500 |
| Lowest listing price | $21,900 (best) | — |
| Median listing price | $26,892 (best) | — |
| Highest listing price | $42,900 (best) | — |
| For sale now | 10 (best) | 0 |
Fuel economy & range
| Spec | Cadillac CT4Luxury | Lexus IS350350 F SPORT Design |
|---|---|---|
| Combined MPG | 26 MPG (best) | 23 MPG |
| City MPG | 22 MPG (best) | 20 MPG |
| Highway MPG | 32 MPG (best) | 28 MPG |
| Fuel tank | 17 gal | 17.4 gal (best) |
Performance
| Spec | Cadillac CT4Luxury | Lexus IS350350 F SPORT Design |
|---|---|---|
| Horsepower | 237 hp | 311 hp (best) |
| Torque | 258 lb-ft | 280 lb-ft (best) |
| Engine size | 2 L | 3.5 L (best) |
| Cylinders | I4 | V6 |
Size & capability
| Spec | Cadillac CT4Luxury | Lexus IS350350 F SPORT Design |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Cargo volume | 10.7 cu ft | 10.8 cu ft (best) |
| Curb weight | 3,422 lbs (best) | 3,792 lbs |
| Wheelbase | 109 in | 110.2 in (best) |
| Length | 187.2 in (best) | 185.8 in |
| Width | 71.4 in | 72.4 in (best) |
| Height | 56 in | 56.5 in (best) |
Safety & recalls
| Spec | Cadillac CT4Luxury | Lexus IS350350 F SPORT Design |
|---|---|---|
| NHTSA overall | Not Rated | — |
| Frontal crash (driver) | Not Rated | — |
| Frontal crash (passenger) | Not Rated | — |
| Side crash (driver) | Not Rated | — |
| Side crash (passenger) | Not Rated | — |
| Side pole | Not Rated | — |
| Rollover | Not Rated | — |
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Cadillac CT4 | Lexus IS350 |
|---|---|---|
| 1 | Luxury $35,600 MSRP(Currently comparing) | 350 F SPORT Design $45,500 MSRP(Currently comparing) |
| 2 | Premium Luxury $39,900 MSRP | 350 F SPORT Design $47,500 MSRP |
| 3 | Sport $43,800 MSRP | 350 F SPORT $47,950 MSRP |
| 4 | V $50,000 MSRP | 350 F SPORT $49,950 MSRP |
| 5 | V Blackwing $62,700 MSRP | — |
Live inventory
Cadillac CT410 for sale
See all
Used2021 Cadillac CT4
Premium Luxury
Evergreen Metallic•Whisper Beige With Jet Black Accents66,571 mi$23,990Drive Appeal
Eden Prairie, MN
Used2023 Cadillac CT4
Premium Luxury
Gray•Jet Black with Jet Black accents21,760 mi$30,398Kendall Hyundai
Miami, FL
Used2020 Cadillac CT4
Premium Luxury
Summit White•Jet Black With Jet Black Accents40,015 mi$22,481Smythe Volvo Cars
Summit, NJ
Certified2023 Cadillac CT4
Premium Luxury
Black Raven56,110 mi$29,033Bayway Cadillac of the Woodlands
The Woodlands, TX
Used2021 Cadillac CT4
Sport
Black•Black78,315 mi$24,283Hanania INFINITI of Orange Park
Jacksonville, FL
Used2022 Cadillac CT4
Sport
Infrared Tintcoat•Jet Black w/Jet Black Accents35,079 mi$28,999Countryside Chevrolet
Byron, GA
Cadillac CT4 vs Lexus IS350 FAQ
- Which is better: 2026 Cadillac CT4 or 2026 Lexus IS350?
- It depends on priorities. OpenDealer compares 2026 Cadillac CT4 vs 2026 Lexus IS350 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Cadillac CT4 or 2026 Lexus IS350?
- Based on starting MSRP, the 2026 Cadillac CT4 starts lower at $35,600. Live Cadillac CT4 listings start at $21,900.
- Which has better startingMsrp: 2026 Cadillac CT4 or 2026 Lexus IS350?
- The 2026 Cadillac CT4 leads on startingMsrp in this comparison (35,600).
- Which has better combinedMpg: 2026 Cadillac CT4 or 2026 Lexus IS350?
- The 2026 Cadillac CT4 leads on combinedMpg in this comparison (26).
- Which has better horsepower: 2026 Cadillac CT4 or 2026 Lexus IS350?
- The 2026 Cadillac CT4 leads on horsepower in this comparison (472).
- How do the NHTSA safety ratings compare for 2026 Cadillac CT4 vs 2026 Lexus IS350?
- NHTSA overall crash-test ratings in this comparison: Cadillac CT4 (Not Rated/5 NHTSA overall).