Chevrolet Silverado 2500 HD vs Isuzu i-350
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2006 Isuzu i-350
Overview
| Spec | Chevrolet Silverado 2500 HDWork Truck | Isuzu i-350i-350 LS |
|---|---|---|
| Selected trim | Work Truck | i-350 LS |
| Body style | Truck (Regular Cab) | Truck (Crew Cab) |
| Drivetrain | rear wheel drive | four wheel drive |
| Fuel type | regular unleaded | regular unleaded |
| Transmission | 10-speed shiftable automatic | 4-speed automatic |
| Engine type | gas | gas |
| Model year | 2026 | 2006 |
Pricing & market
| Spec | Chevrolet Silverado 2500 HDWork Truck | Isuzu i-350i-350 LS |
|---|---|---|
| MSRP | $45,900 | $27,358 (best) |
| Lowest listing price | $26,394 (best) | — |
| Median listing price | $67,987 (best) | — |
| Highest listing price | $84,184 (best) | — |
| For sale now | 17 (best) | 0 |
Fuel economy & range
| Spec | Chevrolet Silverado 2500 HDWork Truck | Isuzu i-350i-350 LS |
|---|---|---|
| Combined MPG | — | 17 MPG (best) |
| City MPG | — | 16 MPG (best) |
| Highway MPG | — | 21 MPG (best) |
| Fuel tank | 36 gal (best) | 19.6 gal |
Performance
| Spec | Chevrolet Silverado 2500 HDWork Truck | Isuzu i-350i-350 LS |
|---|---|---|
| Horsepower | 401 hp (best) | 220 hp |
| Torque | 464 lb-ft (best) | 225 lb-ft |
| Engine size | 6.6 L (best) | 3.5 L |
| Cylinders | V8 | I5 |
Size & capability
| Spec | Chevrolet Silverado 2500 HDWork Truck | Isuzu i-350i-350 LS |
|---|---|---|
| Seating | 3 seats | 5 seats (best) |
| Doors | 2 | 4 (best) |
| Towing capacity | 14,500 lbs (best) | 4,000 lbs |
| Payload | 3,759 lbs (best) | 1,190 lbs |
| Curb weight | 6,203 lbs | 3,802 lbs (best) |
| Ground clearance | 10.2 in (best) | 8.7 in |
| Wheelbase | 142 in (best) | 125.9 in |
| Length | 235.6 in (best) | 207.1 in |
| Width | 81.8 in (best) | 68.6 in |
| Height | 79.9 in (best) | 67.9 in |
Safety & recalls
| Spec | Chevrolet Silverado 2500 HDWork Truck | Isuzu i-350i-350 LS |
|---|---|---|
| Frontal crash (driver) | — | 5 / 5 ★ (best) |
| Frontal crash (passenger) | — | 5 / 5 ★ (best) |
| Rollover | — | 4 / 5 ★ (best) |
| Open recalls (YMM scope) | None reported (best) | 2 |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Chevrolet Silverado 2500 HD | Isuzu i-350 |
|---|---|---|
| 1 | Work Truck $45,900 MSRP(Currently comparing) | i-350 LS $27,358 MSRP(Currently comparing) |
| 2 | Work Truck $47,600 MSRP | — |
| 3 | Work Truck $47,800 MSRP | — |
| 4 | Work Truck $49,400 MSRP | — |
| 5 | Work Truck $49,600 MSRP | — |
| 6 | Work Truck $48,700 MSRP | — |
| 7 | Work Truck $50,400 MSRP | — |
| 8 | Work Truck $50,600 MSRP | — |
| 9 | Work Truck $52,200 MSRP | — |
| 10 | Work Truck $52,400 MSRP | — |
| 11 | Custom $49,200 MSRP | — |
| 12 | Custom $49,400 MSRP | — |
| 13 | Custom $51,000 MSRP | — |
| 14 | Custom $51,200 MSRP | — |
| 15 | Custom $52,000 MSRP | — |
| 16 | Custom $52,200 MSRP | — |
| 17 | Custom $53,800 MSRP | — |
| 18 | Custom $54,000 MSRP | — |
| 19 | LT $52,600 MSRP | — |
| 20 | LT $54,600 MSRP | — |
| 21 | LT $54,800 MSRP | — |
| 22 | LT $56,400 MSRP | — |
| 23 | LT $56,600 MSRP | — |
| 24 | LTZ $63,300 MSRP | — |
| 25 | LTZ $63,500 MSRP | — |
| 26 | ZR2 $73,200 MSRP | — |
| 27 | High Country $73,600 MSRP | — |
| 28 | High Country $73,800 MSRP | — |
Live inventory
Chevrolet Silverado 2500 HD17 for sale
See all
New2026 Chevrolet Silverado 2500 HD
LT
Summit White•Jet Black, Leather-Appointed Front Outboard Seat Trim10 mi$72,539MSRP $78,140Jay Hatfield Chevrolet Chanute
Chanute, KS
New2026 Chevrolet Silverado 2500 HD
LT
Summit White•Jet Black, Cloth Seat Trim11 mi$66,714MSRP $75,315Jay Hatfield Chevrolet Chanute
Chanute, KS
New2026 Chevrolet Silverado 2500 HD
LTZ
Cypress Gray•Jet Black, Perforated Leather-Appointed Front Outboard Seat TrimN/A$84,184MSRP $84,785Jay Hatfield Chevrolet Chanute
Chanute, KS
New2026 Chevrolet Silverado 2500 HD
LTZ
Sterling Gray Metallic•Jet Black, Perforated Leather-Appointed Front Outboard Seat TrimN/A$79,389MSRP $84,090Jay Hatfield Chevrolet Chanute
Chanute, KS
New2026 Chevrolet Silverado 2500 HD
LTZ
Radiant Red Tintcoat•Gideon/Very Dark Atmosphere, Perforated Leather-Appointed Front Outboard Seat TrimN/A$78,149MSRP $83,750Jay Hatfield Chevrolet Chanute
Chanute, KS
New2026 Chevrolet Silverado 2500 HD
Custom
Lakeshore Blue Metallic•Jet Black, Cloth Seat TrimN/A$67,072MSRP $70,840Jay Hatfield Chevrolet of Pittsburg
Frontenac, KS
Chevrolet Silverado 2500 HD vs Isuzu i-350 FAQ
- Which is better: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- It depends on priorities. OpenDealer compares 2026 Chevrolet Silverado 2500 HD vs 2006 Isuzu i-350 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- Based on starting MSRP, the 2006 Isuzu i-350 starts lower at $27,358. Live Chevrolet Silverado 2500 HD listings start at $26,394.
- Which has better startingMsrp: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- The 2006 Isuzu i-350 leads on startingMsrp in this comparison (27,358).
- Which has better combinedMpg: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- The 2006 Isuzu i-350 leads on combinedMpg in this comparison (17).
- Which has better horsepower: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- The 2026 Chevrolet Silverado 2500 HD leads on horsepower in this comparison (401).
- Which has better seats: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- The 2026 Chevrolet Silverado 2500 HD leads on seats in this comparison (6).
- Which has better maxTowingLbs: 2026 Chevrolet Silverado 2500 HD or 2006 Isuzu i-350?
- The 2026 Chevrolet Silverado 2500 HD leads on maxTowingLbs in this comparison (20,000).