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Lexus IS300 vs Toyota Avalon

Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.

Vehicles

Lexus logo

2025 Lexus IS300

Toyota logo

2022 Toyota Avalon

Overview

SpecLexus IS300300Toyota AvalonXLE
Selected trim300XLE
Body styleSedanSedan
Drivetrainrear wheel drivefront wheel drive
Fuel typepremium unleaded (required)regular unleaded
Transmission8-speed shiftable automatic8-speed shiftable automatic
Engine typegasgas
Model year20252022

Pricing & market

SpecLexus IS300300Toyota AvalonXLE
MSRP$40,535$36,825 (best)
Lowest listing price$15,117 (best)
Median listing price$25,943 (best)
Highest listing price$36,969 (best)
For sale now010 (best)

Fuel economy & range

SpecLexus IS300300Toyota AvalonXLE
Combined MPG25 MPG26 MPG (best)
City MPG21 MPG22 MPG (best)
Highway MPG31 MPG32 MPG (best)
Fuel tank17.4 gal (best)14.5 gal

Performance

SpecLexus IS300300Toyota AvalonXLE
Horsepower241 hp301 hp (best)
Torque258 lb-ft267 lb-ft (best)
Engine size2 L3.5 L (best)
CylindersI4V6

Size & capability

SpecLexus IS300300Toyota AvalonXLE
Seating5 seats5 seats
Doors44
Cargo volume10.8 cu ft16.1 cu ft (best)
Payload975 lbs (best)
Curb weight3,715 lbs3,570 lbs (best)
Ground clearance5.5 in (best)5.3 in
Wheelbase110.2 in113 in (best)
Length185.4 in195.9 in (best)
Width72.4 in72.8 in (best)
Height56.5 in56.5 in

Safety & recalls

SpecLexus IS300300Toyota AvalonXLE
NHTSA overall5 / 5 ★ (best)
Frontal crash (driver)4 / 5 ★ (best)
Frontal crash (passenger)4 / 5 ★ (best)
Side crash (driver)5 / 5 ★ (best)
Side crash (passenger)5 / 5 ★ (best)
Side pole5 / 5 ★ (best)
Rollover4 / 5 ★ (best)
Open recalls (YMM scope)None reportedNone reported

Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.

Trim overview

All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.

TrimLexus IS300Toyota Avalon
1

300

$40,535 MSRP(Currently comparing)

XLE

$36,825 MSRP(Currently comparing)

2

300

$42,535 MSRP

XLE

$37,850 MSRP

3

300 F SPORT Design

$42,505 MSRP

XSE Nightshade

$41,200 MSRP

4

300 F SPORT Design

$44,545 MSRP

Limited

$43,125 MSRP

5

300 F SPORT

$44,580 MSRP

Touring

$43,525 MSRP

6

300 F SPORT

$46,620 MSRP

Limited

$44,150 MSRP

Live inventory

Lexus IS300 vs Toyota Avalon FAQ

Which is better: 2025 Lexus IS300 or 2022 Toyota Avalon?
It depends on priorities. OpenDealer compares 2025 Lexus IS300 vs 2022 Toyota Avalon on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
Which costs less: 2025 Lexus IS300 or 2022 Toyota Avalon?
Based on starting MSRP, the 2022 Toyota Avalon starts lower at $36,825. Live Toyota Avalon listings start at $15,117.
Which has better startingMsrp: 2025 Lexus IS300 or 2022 Toyota Avalon?
The 2022 Toyota Avalon leads on startingMsrp in this comparison (36,825).
Which has better combinedMpg: 2025 Lexus IS300 or 2022 Toyota Avalon?
The 2022 Toyota Avalon leads on combinedMpg in this comparison (44).
Which has better horsepower: 2025 Lexus IS300 or 2022 Toyota Avalon?
The 2022 Toyota Avalon leads on horsepower in this comparison (301).
How do the NHTSA safety ratings compare for 2025 Lexus IS300 vs 2022 Toyota Avalon?
NHTSA overall crash-test ratings in this comparison: Toyota Avalon (5/5 NHTSA overall).