Lexus IS350 vs Mercedes-Benz C300
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2026 Mercedes-Benz C300
Overview
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C300C 300 |
|---|---|---|
| Selected trim | 350 F SPORT Design | C 300 |
| Body style | Sedan | Sedan |
| Drivetrain | rear wheel drive | rear wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | 8-speed shiftable automatic | 9-speed shiftable automatic |
| Engine type | gas | mild hybrid |
| Model year | 2026 | 2026 |
Pricing & market
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C300C 300 |
|---|---|---|
| MSRP | $45,500 (best) | $49,650 |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C300C 300 |
|---|---|---|
| Combined MPG | 23 MPG | 29 MPG (best) |
| City MPG | 20 MPG | 25 MPG (best) |
| Highway MPG | 28 MPG | 35 MPG (best) |
| Fuel tank | 17.4 gal | 17.4 gal |
Performance
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C300C 300 |
|---|---|---|
| Horsepower | 311 hp (best) | 255 hp |
| Torque | 280 lb-ft | 295 lb-ft (best) |
| Engine size | 3.5 L (best) | 2 L |
| Cylinders | V6 | I4 |
Size & capability
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C300C 300 |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Cargo volume | 10.8 cu ft | 11.6 cu ft (best) |
| Curb weight | 3,792 lbs (best) | 3,825 lbs |
| Wheelbase | 110.2 in | 112.8 in (best) |
| Length | 185.8 in | 187 in (best) |
| Width | 72.4 in | 74.4 in (best) |
| Height | 56.5 in | 56.6 in (best) |
Safety & recalls
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C300C 300 |
|---|---|---|
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Lexus IS350 | Mercedes-Benz C300 |
|---|---|---|
| 1 | 350 F SPORT Design $45,500 MSRP(Currently comparing) | C 300 $49,650 MSRP(Currently comparing) |
| 2 | 350 F SPORT Design $47,500 MSRP | C 300 4MATIC $51,650 MSRP |
| 3 | 350 F SPORT $47,950 MSRP | — |
| 4 | 350 F SPORT $49,950 MSRP | — |