Lexus IS350 vs Mercedes-Benz C350
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2015 Mercedes-Benz C350
Overview
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C350C 350 |
|---|---|---|
| Selected trim | 350 F SPORT Design | C 350 |
| Body style | Sedan | Coupe |
| Drivetrain | rear wheel drive | rear wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | 8-speed shiftable automatic | 7-speed shiftable automatic |
| Engine type | gas | gas |
| Model year | 2026 | 2015 |
Pricing & market
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C350C 350 |
|---|---|---|
| MSRP | $45,500 | $44,050 (best) |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C350C 350 |
|---|---|---|
| Combined MPG | 22 MPG | 23 MPG (best) |
| City MPG | 19 MPG | 20 MPG (best) |
| Highway MPG | 27 MPG | 28 MPG (best) |
| Fuel tank | 17.4 gal | 17.4 gal |
Performance
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C350C 350 |
|---|---|---|
| Horsepower | 311 hp (best) | 302 hp |
| Torque | 280 lb-ft (best) | 273 lb-ft |
| Engine size | 3.5 L | 3.5 L |
| Cylinders | V6 | V6 |
Size & capability
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C350C 350 |
|---|---|---|
| Seating | 5 seats (best) | 4 seats |
| Doors | 4 (best) | 2 |
| Cargo volume | 10.8 cu ft | 11.7 cu ft (best) |
| Curb weight | 3,792 lbs (best) | — |
| Ground clearance | — | 4 in (best) |
| Wheelbase | 110.2 in (best) | 108.7 in |
| Length | 185.8 in (best) | 180.7 in |
| Width | 72.4 in (best) | 69.7 in |
| Height | 56.5 in (best) | 54.8 in |
Safety & recalls
| Spec | Lexus IS350350 F SPORT Design | Mercedes-Benz C350C 350 |
|---|---|---|
| Open recalls (YMM scope) | None reported (best) | 4 |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Lexus IS350 | Mercedes-Benz C350 |
|---|---|---|
| 1 | 350 F SPORT Design $45,500 MSRP(Currently comparing) | C 350 $44,050 MSRP(Currently comparing) |
| 2 | 350 F SPORT Design $47,500 MSRP | C 350 4MATIC $46,050 MSRP |
| 3 | 350 F SPORT $47,950 MSRP | — |
| 4 | 350 F SPORT $49,950 MSRP | — |
Lexus IS350 vs Mercedes-Benz C350 FAQ
- Which is better: 2026 Lexus IS350 or 2015 Mercedes-Benz C350?
- It depends on priorities. OpenDealer compares 2026 Lexus IS350 vs 2015 Mercedes-Benz C350 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Lexus IS350 or 2015 Mercedes-Benz C350?
- Based on starting MSRP, the 2015 Mercedes-Benz C350 starts lower at $44,050.
- Which has better startingMsrp: 2026 Lexus IS350 or 2015 Mercedes-Benz C350?
- The 2015 Mercedes-Benz C350 leads on startingMsrp in this comparison (44,050).
- Which has better combinedMpg: 2026 Lexus IS350 or 2015 Mercedes-Benz C350?
- The 2015 Mercedes-Benz C350 leads on combinedMpg in this comparison (23).
- Which has better horsepower: 2026 Lexus IS350 or 2015 Mercedes-Benz C350?
- The 2026 Lexus IS350 leads on horsepower in this comparison (311).
- Which has better seats: 2026 Lexus IS350 or 2015 Mercedes-Benz C350?
- The 2026 Lexus IS350 leads on seats in this comparison (5).