Lexus LS500 vs Mercedes-Benz S450
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2020 Mercedes-Benz S450
Overview
| Spec | Lexus LS500500 Heritage Edition | Mercedes-Benz S450S 450 |
|---|---|---|
| Selected trim | 500 Heritage Edition | S 450 |
| Body style | Sedan | Sedan |
| Drivetrain | all wheel drive | rear wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | 10-speed shiftable automatic | 9-speed shiftable automatic |
| Engine type | gas | gas |
| Model year | 2026 | 2020 |
Pricing & market
| Spec | Lexus LS500500 Heritage Edition | Mercedes-Benz S450S 450 |
|---|---|---|
| MSRP | $97,830 | $94,250 (best) |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Lexus LS500500 Heritage Edition | Mercedes-Benz S450S 450 |
|---|---|---|
| Combined MPG | 21 MPG | 22 MPG (best) |
| City MPG | 17 MPG | 19 MPG (best) |
| Highway MPG | 27 MPG | 28 MPG (best) |
| Fuel tank | 21.7 gal (best) | 21.1 gal |
Performance
| Spec | Lexus LS500500 Heritage Edition | Mercedes-Benz S450S 450 |
|---|---|---|
| Horsepower | 416 hp (best) | 362 hp |
| Torque | 442 lb-ft (best) | 369 lb-ft |
| Engine size | 3.4 L (best) | 3 L |
| Cylinders | V6 | V6 |
Size & capability
| Spec | Lexus LS500500 Heritage Edition | Mercedes-Benz S450S 450 |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Cargo volume | 17 cu ft | 18.7 cu ft (best) |
| Curb weight | 4,905 lbs | 4,542 lbs (best) |
| Ground clearance | — | 5 in (best) |
| Wheelbase | 123 in | 124.6 in (best) |
| Length | 206.1 in | 206.9 in (best) |
| Width | 74.8 in | 74.8 in |
| Height | 57.5 in | 58.9 in (best) |
Safety & recalls
| Spec | Lexus LS500500 Heritage Edition | Mercedes-Benz S450S 450 |
|---|---|---|
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Lexus LS500 | Mercedes-Benz S450 |
|---|---|---|
| 1 | 500 Heritage Edition $97,830 MSRP(Currently comparing) | S 450 $94,250 MSRP(Currently comparing) |
| 2 | — | S 450 4MATIC $97,250 MSRP |
Lexus LS500 vs Mercedes-Benz S450 FAQ
- Which is better: 2026 Lexus LS500 or 2020 Mercedes-Benz S450?
- It depends on priorities. OpenDealer compares 2026 Lexus LS500 vs 2020 Mercedes-Benz S450 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Lexus LS500 or 2020 Mercedes-Benz S450?
- Based on starting MSRP, the 2020 Mercedes-Benz S450 starts lower at $94,250.
- Which has better startingMsrp: 2026 Lexus LS500 or 2020 Mercedes-Benz S450?
- The 2020 Mercedes-Benz S450 leads on startingMsrp in this comparison (94,250).
- Which has better combinedMpg: 2026 Lexus LS500 or 2020 Mercedes-Benz S450?
- The 2020 Mercedes-Benz S450 leads on combinedMpg in this comparison (22).
- Which has better horsepower: 2026 Lexus LS500 or 2020 Mercedes-Benz S450?
- The 2026 Lexus LS500 leads on horsepower in this comparison (416).