Lexus LS500h vs Mercedes-Benz S580
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2027 Mercedes-Benz S580
Overview
| Spec | Lexus LS500h500h | Mercedes-Benz S580S 580 4MATIC |
|---|---|---|
| Selected trim | 500h | S 580 4MATIC |
| Body style | Sedan | Sedan |
| Drivetrain | all wheel drive | all wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | electrically variable-speed automatic | 9-speed shiftable automatic |
| Engine type | hybrid | mild hybrid |
| Model year | 2025 | 2027 |
Pricing & market
| Spec | Lexus LS500h500h | Mercedes-Benz S580S 580 4MATIC |
|---|---|---|
| MSRP | $115,210 (best) | $134,600 |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Lexus LS500h500h | Mercedes-Benz S580S 580 4MATIC |
|---|---|---|
| Combined MPG | 25 MPG (best) | 20 MPG |
| City MPG | 22 MPG (best) | 17 MPG |
| Highway MPG | 29 MPG (best) | 27 MPG |
| Fuel tank | 22.2 gal (best) | 20 gal |
Performance
| Spec | Lexus LS500h500h | Mercedes-Benz S580S 580 4MATIC |
|---|---|---|
| Horsepower | 354 hp | 530 hp (best) |
| Torque | — | 553 lb-ft (best) |
| Engine size | 3.5 L | 4 L (best) |
| Cylinders | V6 | V8 |
Size & capability
| Spec | Lexus LS500h500h | Mercedes-Benz S580S 580 4MATIC |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Cargo volume | 15.2 cu ft (best) | 12.5 cu ft |
| Curb weight | 5,093 lbs | 4,795 lbs (best) |
| Ground clearance | 5.8 in (best) | 5.1 in |
| Wheelbase | 123 in | 126.6 in (best) |
| Length | 206.1 in | 209.5 in (best) |
| Width | 74.8 in | 75.6 in (best) |
| Height | 57.5 in | 59.2 in (best) |
Safety & recalls
| Spec | Lexus LS500h500h | Mercedes-Benz S580S 580 4MATIC |
|---|---|---|
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Lexus LS500h | Mercedes-Benz S580 |
|---|---|---|
| 1 | 500h $115,210 MSRP(Currently comparing) | S 580 4MATIC $134,600 MSRP(Currently comparing) |
Lexus LS500h vs Mercedes-Benz S580 FAQ
- Which is better: 2025 Lexus LS500h or 2027 Mercedes-Benz S580?
- It depends on priorities. OpenDealer compares 2025 Lexus LS500h vs 2027 Mercedes-Benz S580 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2025 Lexus LS500h or 2027 Mercedes-Benz S580?
- Based on starting MSRP, the 2025 Lexus LS500h starts lower at $115,210.
- Which has better startingMsrp: 2025 Lexus LS500h or 2027 Mercedes-Benz S580?
- The 2025 Lexus LS500h leads on startingMsrp in this comparison (115,210).
- Which has better combinedMpg: 2025 Lexus LS500h or 2027 Mercedes-Benz S580?
- The 2025 Lexus LS500h leads on combinedMpg in this comparison (25).
- Which has better horsepower: 2025 Lexus LS500h or 2027 Mercedes-Benz S580?
- The 2027 Mercedes-Benz S580 leads on horsepower in this comparison (530).