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Lexus NX300 vs Nissan Murano

Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.

Vehicles

Lexus logo

2021 Lexus NX300

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Nissan logo

2026 Nissan Murano

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Overview

SpecLexus NX300300Nissan MuranoSV
Selected trim300SV
Body styleSUVSUV
Drivetrainfront wheel driveall wheel drive
Fuel typepremium unleaded (required)regular unleaded
Transmission6-speed shiftable automatic9-speed shiftable automatic
Engine typegasgas
Model year20212026

Pricing & market

SpecLexus NX300300Nissan MuranoSV
MSRP$37,610 (best)$41,470
Lowest listing price—$6,946 (best)
Median listing price—$42,589 (best)
Highest listing price—$51,033 (best)
For sale now0155 (best)

Fuel economy & range

SpecLexus NX300300Nissan MuranoSV
Combined MPG25 MPG (best)23 MPG
City MPG22 MPG (best)21 MPG
Highway MPG28 MPG (best)27 MPG
Fuel tank15.9 gal18.7 gal (best)

Performance

SpecLexus NX300300Nissan MuranoSV
Horsepower235 hp241 hp (best)
Torque258 lb-ft260 lb-ft (best)
Engine size2 L2 L
CylindersI4I4

Size & capability

SpecLexus NX300300Nissan MuranoSV
Seating5 seats5 seats
Doors5 (best)4
Cargo volume54.5 cu ft63.5 cu ft (best)
Towing capacity2,000 lbs (best)1,500 lbs
Payload1,150 lbs1,277 lbs (best)
Curb weight3,940 lbs (best)4,323 lbs
Ground clearance6.9 in8.3 in (best)
Wheelbase104.7 in111.2 in (best)
Length182.7 in192.9 in (best)
Width73.6 in78 in (best)
Height64.8 in67.9 in (best)

Safety & recalls

SpecLexus NX300300Nissan MuranoSV
NHTSA overall—5 / 5 ★ (best)
Frontal crash (driver)—5 / 5 ★ (best)
Frontal crash (passenger)—3 / 5 ★ (best)
Side crash (driver)—5 / 5 ★ (best)
Side crash (passenger)—5 / 5 ★ (best)
Side pole—5 / 5 ★ (best)
Rollover—4 / 5 ★ (best)
Open recalls (YMM scope)None reportedNone reported

Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.

Trim overview

All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.

TrimLexus NX300Nissan Murano
1

300

$37,610 MSRP(Currently comparing)

SV

$41,470 MSRP(Currently comparing)

2

300

$39,010 MSRP

SL

$46,560 MSRP

3

300 F SPORT

$39,710 MSRP

Platinum

$49,600 MSRP

4

300 F SPORT

$41,110 MSRP

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5

300 Luxury

$44,060 MSRP

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6

300 Luxury

$45,460 MSRP

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Live inventory

Lexus NX300 vs Nissan Murano FAQ

Which is better: 2021 Lexus NX300 or 2026 Nissan Murano?
It depends on priorities. OpenDealer compares 2021 Lexus NX300 vs 2026 Nissan Murano on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
Which costs less: 2021 Lexus NX300 or 2026 Nissan Murano?
Based on starting MSRP, the 2021 Lexus NX300 starts lower at $37,610. Live Nissan Murano listings start at $6,946.
Which has better startingMsrp: 2021 Lexus NX300 or 2026 Nissan Murano?
The 2021 Lexus NX300 leads on startingMsrp in this comparison (37,610).
Which has better combinedMpg: 2021 Lexus NX300 or 2026 Nissan Murano?
The 2021 Lexus NX300 leads on combinedMpg in this comparison (25).
Which has better horsepower: 2021 Lexus NX300 or 2026 Nissan Murano?
The 2026 Nissan Murano leads on horsepower in this comparison (241).
Which has better maxTowingLbs: 2021 Lexus NX300 or 2026 Nissan Murano?
The 2021 Lexus NX300 leads on maxTowingLbs in this comparison (2,000).
How do the NHTSA safety ratings compare for 2021 Lexus NX300 vs 2026 Nissan Murano?
NHTSA overall crash-test ratings in this comparison: Nissan Murano (5/5 NHTSA overall).