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Lexus RX450hL vs Mercedes-Benz GLE350

Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.

Vehicles

Lexus logo

2022 Lexus RX450hL

Mercedes-Benz logo

2027 Mercedes-Benz GLE350

Overview

SpecLexus RX450hL450hLMercedes-Benz GLE350GLE 350 4MATIC
Selected trim450hLGLE 350 4MATIC
Body styleSUVSUV
Drivetrainall wheel driveall wheel drive
Fuel typepremium unleaded (recommended)premium unleaded (required)
Transmissioncontinuously variable-speed automatic9-speed shiftable automatic
Engine typehybridmild hybrid
Model year20222027

Pricing & market

SpecLexus RX450hL450hLMercedes-Benz GLE350GLE 350 4MATIC
MSRP$52,110 (best)$68,400
For sale now00

Fuel economy & range

SpecLexus RX450hL450hLMercedes-Benz GLE350GLE 350 4MATIC
Combined MPG29 MPG (best)—
City MPG29 MPG (best)—
Highway MPG28 MPG (best)—
Fuel tank17.2 gal22.5 gal (best)

Performance

SpecLexus RX450hL450hLMercedes-Benz GLE350GLE 350 4MATIC
Horsepower308 hp (best)255 hp
Torque247 lb-ft295 lb-ft (best)
Engine size3.5 L (best)2 L
CylindersV6I4

Size & capability

SpecLexus RX450hL450hLMercedes-Benz GLE350GLE 350 4MATIC
Seating6 seats (best)5 seats
Doors5 (best)4
Cargo volume58.5 cu ft74.9 cu ft (best)
Towing capacity—7,700 lbs (best)
Payload1,356 lbs (best)—
Curb weight4,905 lbs (best)4,916 lbs
Ground clearance7.9 in (best)—
Wheelbase109.8 in117.9 in (best)
Length196.9 in (best)193.8 in
Width74.6 in79.7 in (best)
Height67.7 in70.7 in (best)

Safety & recalls

SpecLexus RX450hL450hLMercedes-Benz GLE350GLE 350 4MATIC
Open recalls (YMM scope)None reportedNone reported

Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.

Trim overview

All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.

TrimLexus RX450hLMercedes-Benz GLE350
1

450hL

$52,110 MSRP(Currently comparing)

GLE 350 4MATIC

$68,400 MSRP(Currently comparing)

2

450hL Luxury

$58,110 MSRP

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Lexus RX450hL vs Mercedes-Benz GLE350 FAQ

Which is better: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
It depends on priorities. OpenDealer compares 2022 Lexus RX450hL vs 2027 Mercedes-Benz GLE350 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
Which costs less: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
Based on starting MSRP, the 2022 Lexus RX450hL starts lower at $52,110.
Which has better startingMsrp: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
The 2022 Lexus RX450hL leads on startingMsrp in this comparison (52,110).
Which has better combinedMpg: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
The 2022 Lexus RX450hL leads on combinedMpg in this comparison (29).
Which has better horsepower: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
The 2022 Lexus RX450hL leads on horsepower in this comparison (308).
Which has better seats: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
The 2022 Lexus RX450hL leads on seats in this comparison (6).
Which has better maxTowingLbs: 2022 Lexus RX450hL or 2027 Mercedes-Benz GLE350?
The 2027 Mercedes-Benz GLE350 leads on maxTowingLbs in this comparison (7,700).