Mercedes-Benz C43 AMG vs Mercedes-Benz E450
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2027 Mercedes-Benz E450
Overview
| Spec | Mercedes-Benz C43 AMGAMG C 43 | Mercedes-Benz E450E 450 4MATIC |
|---|---|---|
| Selected trim | AMG C 43 | E 450 4MATIC |
| Body style | Sedan | Sedan |
| Drivetrain | all wheel drive | all wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | 9-speed shiftable automatic | 9-speed shiftable automatic |
| Engine type | mild hybrid | mild hybrid |
| Model year | 2026 | 2027 |
Pricing & market
| Spec | Mercedes-Benz C43 AMGAMG C 43 | Mercedes-Benz E450E 450 4MATIC |
|---|---|---|
| MSRP | $64,150 (best) | $73,700 |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Mercedes-Benz C43 AMGAMG C 43 | Mercedes-Benz E450E 450 4MATIC |
|---|---|---|
| Combined MPG | 22 MPG | 25 MPG (best) |
| City MPG | 19 MPG | 22 MPG (best) |
| Highway MPG | 27 MPG | 31 MPG (best) |
| Fuel tank | 17.4 gal | 17.4 gal |
Performance
| Spec | Mercedes-Benz C43 AMGAMG C 43 | Mercedes-Benz E450E 450 4MATIC |
|---|---|---|
| Horsepower | 416 hp (best) | 375 hp |
| Torque | 369 lb-ft | 369 lb-ft |
| Engine size | 2 L | 3 L (best) |
| Cylinders | I4 | I6 |
Size & capability
| Spec | Mercedes-Benz C43 AMGAMG C 43 | Mercedes-Benz E450E 450 4MATIC |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Cargo volume | 11.6 cu ft | 12.7 cu ft (best) |
| Curb weight | 4,165 lbs (best) | 4,376 lbs |
| Wheelbase | 112.8 in | 116.6 in (best) |
| Length | 188.6 in | 194.9 in (best) |
| Width | 74.4 in (best) | 74 in |
| Height | 57.1 in | 57.9 in (best) |
Safety & recalls
| Spec | Mercedes-Benz C43 AMGAMG C 43 | Mercedes-Benz E450E 450 4MATIC |
|---|---|---|
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Mercedes-Benz C43 AMG | Mercedes-Benz E450 |
|---|---|---|
| 1 | AMG C 43 $64,150 MSRP(Currently comparing) | E 450 4MATIC $73,700 MSRP(Currently comparing) |
| 2 | — | E 450 4MATIC All-Terrain $80,000 MSRP |
Mercedes-Benz C43 AMG vs Mercedes-Benz E450 FAQ
- Which is better: 2026 Mercedes-Benz C43 AMG or 2027 Mercedes-Benz E450?
- It depends on priorities. OpenDealer compares 2026 Mercedes-Benz C43 AMG vs 2027 Mercedes-Benz E450 on MSRP, fuel economy, horsepower, seating, towing, NHTSA safety ratings, and live market prices so you can weigh the tradeoffs.
- Which costs less: 2026 Mercedes-Benz C43 AMG or 2027 Mercedes-Benz E450?
- Based on starting MSRP, the 2026 Mercedes-Benz C43 AMG starts lower at $64,150.
- Which has better startingMsrp: 2026 Mercedes-Benz C43 AMG or 2027 Mercedes-Benz E450?
- The 2026 Mercedes-Benz C43 AMG leads on startingMsrp in this comparison (64,150).
- Which has better combinedMpg: 2026 Mercedes-Benz C43 AMG or 2027 Mercedes-Benz E450?
- The 2027 Mercedes-Benz E450 leads on combinedMpg in this comparison (25).
- Which has better horsepower: 2026 Mercedes-Benz C43 AMG or 2027 Mercedes-Benz E450?
- The 2026 Mercedes-Benz C43 AMG leads on horsepower in this comparison (416).
- Which has better seats: 2026 Mercedes-Benz C43 AMG or 2027 Mercedes-Benz E450?
- The 2027 Mercedes-Benz E450 leads on seats in this comparison (7).