Mercedes-Benz E450 vs Mercedes-Benz S500
Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.
Vehicles
Vehicles
2027 Mercedes-Benz S500
Overview
| Spec | Mercedes-Benz E450E 450 4MATIC | Mercedes-Benz S500S 500 4MATIC Sedan |
|---|---|---|
| Selected trim | E 450 4MATIC | S 500 4MATIC Sedan |
| Body style | Sedan | Sedan |
| Drivetrain | all wheel drive | all wheel drive |
| Fuel type | premium unleaded (required) | premium unleaded (required) |
| Transmission | 9-speed automatic | 9-speed automatic |
| Engine type | mild hybrid | mild hybrid |
| Model year | 2027 | 2027 |
Pricing & market
| Spec | Mercedes-Benz E450E 450 4MATIC | Mercedes-Benz S500S 500 4MATIC Sedan |
|---|---|---|
| MSRP | $0 | $0 |
| For sale now | 0 | 0 |
Fuel economy & range
| Spec | Mercedes-Benz E450E 450 4MATIC | Mercedes-Benz S500S 500 4MATIC Sedan |
|---|---|---|
| Combined MPG | 25 MPG (best) | 23 MPG |
| City MPG | 22 MPG (best) | 20 MPG |
| Highway MPG | 31 MPG (best) | 29 MPG |
| Fuel tank | 17 gal | 20 gal (best) |
Performance
| Spec | Mercedes-Benz E450E 450 4MATIC | Mercedes-Benz S500S 500 4MATIC Sedan |
|---|---|---|
| Horsepower | 375 hp | 442 hp (best) |
| Torque | 369 lb-ft | 443 lb-ft (best) |
| Engine size | 3 L | 3 L |
| Cylinders | I6 | I6 |
Size & capability
| Spec | Mercedes-Benz E450E 450 4MATIC | Mercedes-Benz S500S 500 4MATIC Sedan |
|---|---|---|
| Seating | 5 seats | 5 seats |
| Doors | 4 | 4 |
| Curb weight | 4,376 lbs (best) | 4,861 lbs |
| Ground clearance | — | 5 in (best) |
| Wheelbase | 117 in | 127 in (best) |
| Length | 195 in | 209 in (best) |
| Width | 74 in | 76 in (best) |
| Height | 58 in | 59 in (best) |
Safety & recalls
| Spec | Mercedes-Benz E450E 450 4MATIC | Mercedes-Benz S500S 500 4MATIC Sedan |
|---|---|---|
| Open recalls (YMM scope) | None reported | None reported |
Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.
Trim overview
All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.
| Trim | Mercedes-Benz E450 | Mercedes-Benz S500 |
|---|---|---|
| 1 | E 450 4MATIC $0 MSRP(Currently comparing) | S 500 4MATIC Sedan $0 MSRP(Currently comparing) |
| 2 | E 450 4MATIC All-Terrain Wagon $0 MSRP | — |