Mercedes-Benz E450 vs Ram 2500

Side-by-side comparison from manufacturer specifications, NHTSA safety data, and live dealer listings.

Vehicles

2027 Mercedes-Benz E450

Trim

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2026 Ram 2500

Trim

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Overview

Spec	Mercedes-Benz E450E 450 4MATIC	Ram 2500Tradesman
Selected trim	E 450 4MATIC	Tradesman
Body style	Sedan	Truck (Regular Cab)
Drivetrain	all wheel drive	rear wheel drive
Fuel type	premium unleaded (required)	regular unleaded
Transmission	9-speed automatic	8-speed shiftable automatic
Engine type	mild hybrid	gas
Model year	2027	2026

Pricing & market

Spec	Mercedes-Benz E450E 450 4MATIC	Ram 2500Tradesman
MSRP	$0 (best)	$46,485
Lowest listing price	—	$24,003 (best)
Median listing price	—	$64,345 (best)
Highest listing price	—	$98,072 (best)
For sale now	0	32 (best)

Fuel economy & range

Spec	Mercedes-Benz E450E 450 4MATIC	Ram 2500Tradesman
Combined MPG	25 MPG (best)	—
City MPG	22 MPG (best)	—
Highway MPG	31 MPG (best)	—
Fuel tank	17 gal	32 gal (best)

Performance

Spec	Mercedes-Benz E450E 450 4MATIC	Ram 2500Tradesman
Horsepower	375 hp	405 hp (best)
Torque	369 lb-ft	429 lb-ft (best)
Engine size	3 L	6.4 L (best)
Cylinders	I6	V8

Size & capability

Spec	Mercedes-Benz E450E 450 4MATIC	Ram 2500Tradesman
Seating	5 seats (best)	3 seats
Doors	4 (best)	2
Curb weight	4,376 lbs (best)	—
Ground clearance	—	13 in (best)
Wheelbase	117 in	140.5 in (best)
Length	195 in	232 in (best)
Width	74 in	79.4 in (best)
Height	58 in	78 in (best)

Safety & recalls

Spec	Mercedes-Benz E450E 450 4MATIC	Ram 2500Tradesman
NHTSA overall	—	4 / 5 ★ (best)
Frontal crash (driver)	—	4 / 5 ★ (best)
Frontal crash (passenger)	—	5 / 5 ★ (best)
Side crash (driver)	—	5 / 5 ★ (best)
Side crash (passenger)	—	5 / 5 ★ (best)
Side pole	—	5 / 5 ★ (best)
Rollover	—	3 / 5 ★ (best)
Open recalls (YMM scope)	None reported (best)	6

Highlighted values indicate the better figure for that spec when a clear winner exists. Specs reflect the selected trim for each vehicle. Drag a vehicle header to reorder columns. MSRP and specifications are manufacturer data; listing prices and inventory come from live dealer listings. Safety ratings are from NHTSA.

Trim overview

All available trims with MSRP. The trim selected above is highlighted; comparison specs use that selection.

Trim	Mercedes-Benz E450	Ram 2500
1	E 450 4MATIC $0 MSRP(Currently comparing)	Tradesman $46,485 MSRP(Currently comparing)
2	E 450 4MATIC All-Terrain Wagon $0 MSRP	Tradesman $50,105 MSRP
3	—	Tradesman $50,305 MSRP
4	—	Tradesman $49,415 MSRP
5	—	Tradesman $53,035 MSRP
6	—	Tradesman $53,235 MSRP
7	—	Big Horn $50,235 MSRP
8	—	Big Horn $53,855 MSRP
9	—	Big Horn $54,055 MSRP
10	—	Big Horn $53,165 MSRP
11	—	Big Horn $56,785 MSRP
12	—	Big Horn $56,985 MSRP
13	—	Lone Star $50,235 MSRP
14	—	Lone Star $53,855 MSRP
15	—	Lone Star $54,055 MSRP
16	—	Lone Star $53,165 MSRP
17	—	Lone Star $56,785 MSRP
18	—	Lone Star $56,985 MSRP
19	—	Black Express $52,600 MSRP
20	—	Black Express $52,800 MSRP
21	—	Black Express $55,530 MSRP
22	—	Black Express $55,730 MSRP
23	—	Warlock $56,030 MSRP
24	—	Laramie $61,940 MSRP
25	—	Laramie $62,140 MSRP
26	—	Laramie $64,870 MSRP
27	—	Laramie $65,070 MSRP
28	—	Laramie $79,380 MSRP
29	—	Rebel $69,385 MSRP
30	—	Power Wagon $72,880 MSRP
31	—	Limited $73,950 MSRP
32	—	Limited $74,240 MSRP
33	—	Limited $76,880 MSRP
34	—	Limited $77,170 MSRP
35	—	Limited $91,680 MSRP
36	—	Limited Longhorn $73,950 MSRP
37	—	Limited Longhorn $74,240 MSRP
38	—	Limited Longhorn $76,880 MSRP
39	—	Limited Longhorn $77,170 MSRP
40	—	Limited Longhorn $91,680 MSRP