2022 Mercedes-Benz CLS450
1 trim · Sedan
Starting MSRP
$72,950
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Pricing
How much should you pay for the Mercedes-Benz CLS450? Select a trim to update purchase and lease estimates.
MSRP by trim
$72,950
Starting MSRP
Purchase information
Based on CLS 450 4MATIC
Total price (CLS 450 4MATIC MSRP)
$72,950
Typical monthly
$1,444/mo
Avg. APR
7.00%
60-month loan estimate for good credit (rates as of 2026-08-23). Not a credit offer; actual APR varies by lender, credit, and dealer.
Open loan calculatorCompare 2022 Mercedes-Benz CLS450 trims
CLS 450 4MATIC
- MSRP
- $72,950
- Fuel economy (city/hwy)
- 22/30
- Horsepower
- 362 hp
- Torque
- 369 lb-ft
- Engine
- 3L I6 mild hybrid
- Seating
- 5
- Drivetrain
- AWD
- Cargo (cu ft)
- 11.9
- Max towing
- —
| Spec | CLS 450 4MATIC |
|---|---|
| MSRP | $72,950 |
| Fuel economy (city/hwy) | 22/30 |
| Horsepower | 362 hp |
| Torque | 369 lb-ft |
| Engine | 3L I6 mild hybrid |
| Seating | 5 |
| Drivetrain | AWD |
| Cargo (cu ft) | 11.9 |
| Max towing | — |
Manufacturer specifications by trim and drivetrain. Same trim names with different MSRPs are distinct FWD/AWD (or other drivetrain) configurations from the catalog. MSRP excludes destination fees, taxes, and dealer-installed options.
Full specifications
Engine & drivetrain
- Engine type
- mild hybrid
- Fuel type
- premium unleaded (required)
- Cylinders
- I6
- Displacement
- 3 L
- Horsepower
- 362 hp
- Torque
- 369 lb-ft
- Transmission
- 9-speed shiftable automatic
- Drivetrain
- all wheel drive
Dimensions
- Body type
- Sedan
- Doors
- 4
- Seating
- 5
- Length
- 198.8 in
- Width
- 73.8 in
- Height
- 56.6 in
- Wheelbase
- 115.7 in
- Ground clearance
- 3.9 in
Capacity & weight
- Cargo capacity
- 11.9 cu ft
- Curb weight
- 4,255 lbs
- Fuel tank
- 21.1 gal
Fuel economy & EV
- Combined MPG
- 25
- City MPG
- 22
- Highway MPG
- 30
| Spec | Value |
|---|---|
| Engine & drivetrain | |
| Engine type | mild hybrid |
| Fuel type | premium unleaded (required) |
| Cylinders | I6 |
| Displacement | 3 L |
| Horsepower | 362 hp |
| Torque | 369 lb-ft |
| Transmission | 9-speed shiftable automatic |
| Drivetrain | all wheel drive |
| Dimensions | |
| Body type | Sedan |
| Doors | 4 |
| Seating | 5 |
| Length | 198.8 in |
| Width | 73.8 in |
| Height | 56.6 in |
| Wheelbase | 115.7 in |
| Ground clearance | 3.9 in |
| Capacity & weight | |
| Cargo capacity | 11.9 cu ft |
| Curb weight | 4,255 lbs |
| Fuel tank | 21.1 gal |
| Fuel economy & EV | |
| Combined MPG | 25 |
| City MPG | 22 |
| Highway MPG | 30 |
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2022 Mercedes-Benz CLS450 FAQ
- How much does the 2022 Mercedes-Benz CLS450 cost?
- The 2022 Mercedes-Benz CLS450 has a starting MSRP of $72,950. Trim pricing includes CLS 450 4MATIC from $72,950.
- What is the fuel economy of the 2022 Mercedes-Benz CLS450?
- The 2022 Mercedes-Benz CLS450 achieves up to 25 MPG combined (EPA estimate), depending on trim and configuration.
- How much cargo space does the 2022 Mercedes-Benz CLS450 have?
- The 2022 Mercedes-Benz CLS450 offers up to 11.9 cubic feet of cargo capacity, depending on trim and seating configuration.
- How many trims does the 2022 Mercedes-Benz CLS450 come in?
- The 2022 Mercedes-Benz CLS450 is available in 1 trim across Sedan body styles with all wheel drive.