How much does the 2016 Lexus IS350 cost?

The 2016 Lexus IS350 has a starting MSRP of $40,870, ranging up to $43,035 for the top trim. Trim pricing includes 350 from $40,870.

What is the fuel economy of the 2016 Lexus IS350?

The 2016 Lexus IS350 achieves up to 22 MPG combined (EPA estimate), depending on trim and configuration.

How much cargo space does the 2016 Lexus IS350 have?

The 2016 Lexus IS350 offers up to 13.8 cubic feet of cargo capacity, depending on trim and seating configuration.

Is the 2016 Lexus IS350 safe?

The 2016 Lexus IS350 earned an overall rating of 5 out of 5 stars in NHTSA crash testing.

How many trims does the 2016 Lexus IS350 come in?

The 2016 Lexus IS350 is available in 1 trim (2 total configurations) across Sedan body styles with rear wheel drive, all wheel drive.

2016 Lexus IS350

1 trim · 2 configurations · Sedan

Starting MSRP

$40,870 – $43,035

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NHTSA safety

★★★★★

5 / 5 overall

Frontal (driver)★★★★☆

Frontal (passenger)★★★★☆

Side (driver)★★★★★

Side (passenger)★★★★★

Rollover★★★★★

Source: NHTSA

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Pricing

How much should you pay for the Lexus IS350? Select a trim to update purchase and lease estimates.

MSRP by trim

$40,870

Starting MSRP

Purchase information

Based on 350

Total price (350 MSRP)

$40,870

Typical monthly

$809/mo

Avg. APR

7.00%

60-month loan estimate for good credit (rates as of 2026-08-23). Not a credit offer; actual APR varies by lender, credit, and dealer.

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Compare 2016 Lexus IS350 trims

350 RWD
MSRP
$40,870
Fuel economy (city/hwy)
19/28
Horsepower
306 hp
Torque
277 lb-ft
Engine
3.5L V6 gas
Seating
5
Drivetrain
RWD
Cargo (cu ft)
13.8
Max towing
—
350 AWD
MSRP
$43,035
Fuel economy (city/hwy)
19/26
Horsepower
306 hp
Torque
277 lb-ft
Engine
3.5L V6 gas
Seating
5
Drivetrain
AWD
Cargo (cu ft)
13.8
Max towing
—

Compare 2016 Lexus IS350 trim specifications
Spec	350 RWD	350 AWD
MSRP	$40,870	$43,035
Fuel economy (city/hwy)	19/28	19/26
Horsepower	306 hp	306 hp
Torque	277 lb-ft	277 lb-ft
Engine	3.5L V6 gas	3.5L V6 gas
Seating	5	5
Drivetrain	RWD	AWD
Cargo (cu ft)	13.8	13.8
Max towing	—	—

Manufacturer specifications by trim and drivetrain. Same trim names with different MSRPs are distinct FWD/AWD (or other drivetrain) configurations from the catalog. MSRP excludes destination fees, taxes, and dealer-installed options.

Full specifications

Engine & drivetrain

Engine type: 350 RWDgas
350 AWDgas
Fuel type: 350 RWDpremium unleaded (required)
350 AWDpremium unleaded (required)
Cylinders: 350 RWDV6
350 AWDV6
Displacement: 350 RWD3.5 L
350 AWD3.5 L
Horsepower: 350 RWD306 hp
350 AWD306 hp
Torque: 350 RWD277 lb-ft
350 AWD277 lb-ft
Transmission: 350 RWD8-speed shiftable automatic
350 AWD6-speed shiftable automatic
Drivetrain: 350 RWDrear wheel drive
350 AWDall wheel drive

Dimensions

Body type: 350 RWDSedan
350 AWDSedan
Doors: 350 RWD4
350 AWD4
Seating: 350 RWD5
350 AWD5
Length: 350 RWD183.7 in
350 AWD183.7 in
Width: 350 RWD71.3 in
350 AWD71.3 in
Height: 350 RWD56.3 in
350 AWD56.3 in
Wheelbase: 350 RWD110.2 in
350 AWD110.2 in
Ground clearance: 350 RWD5.3 in
350 AWD5.1 in

Capacity & weight

Cargo capacity: 350 RWD13.8 cu ft
350 AWD13.8 cu ft
Max payload: 350 RWD1,037 lbs
350 AWD949 lbs
Curb weight: 350 RWD3,593 lbs
350 AWD3,737 lbs
Fuel tank: 350 RWD17.4 gal
350 AWD17.4 gal

Fuel economy & EV

Combined MPG: 350 RWD22
350 AWD21
City MPG: 350 RWD19
350 AWD19
Highway MPG: 350 RWD28
350 AWD26

Full specifications by trim
Spec	350 RWD	350 AWD
Engine & drivetrain
Engine type	gas	gas
Fuel type	premium unleaded (required)	premium unleaded (required)
Cylinders	V6	V6
Displacement	3.5 L	3.5 L
Horsepower	306 hp	306 hp
Torque	277 lb-ft	277 lb-ft
Transmission	8-speed shiftable automatic	6-speed shiftable automatic
Drivetrain	rear wheel drive	all wheel drive
Dimensions
Body type	Sedan	Sedan
Doors	4	4
Seating	5	5
Length	183.7 in	183.7 in
Width	71.3 in	71.3 in
Height	56.3 in	56.3 in
Wheelbase	110.2 in	110.2 in
Ground clearance	5.3 in	5.1 in
Capacity & weight
Cargo capacity	13.8 cu ft	13.8 cu ft
Max payload	1,037 lbs	949 lbs
Curb weight	3,593 lbs	3,737 lbs
Fuel tank	17.4 gal	17.4 gal
Fuel economy & EV
Combined MPG	22	21
City MPG	19	19
Highway MPG	28	26

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2016 Lexus IS350 FAQ

How much does the 2016 Lexus IS350 cost?: The 2016 Lexus IS350 has a starting MSRP of $40,870, ranging up to $43,035 for the top trim. Trim pricing includes 350 from $40,870.
What is the fuel economy of the 2016 Lexus IS350?: The 2016 Lexus IS350 achieves up to 22 MPG combined (EPA estimate), depending on trim and configuration.
How much cargo space does the 2016 Lexus IS350 have?: The 2016 Lexus IS350 offers up to 13.8 cubic feet of cargo capacity, depending on trim and seating configuration.
Is the 2016 Lexus IS350 safe?: The 2016 Lexus IS350 earned an overall rating of 5 out of 5 stars in NHTSA crash testing.
How many trims does the 2016 Lexus IS350 come in?: The 2016 Lexus IS350 is available in 1 trim (2 total configurations) across Sedan body styles with rear wheel drive, all wheel drive.