How much does the 2026 Mercedes-Benz E450 cost?

The 2026 Mercedes-Benz E450 has a starting MSRP of $72,300, ranging up to $78,300 for the top trim. Trim pricing includes E 450 4MATIC from $72,300.

What is the fuel economy of the 2026 Mercedes-Benz E450?

The 2026 Mercedes-Benz E450 achieves up to 25 MPG combined (EPA estimate), depending on trim and configuration.

How much cargo space does the 2026 Mercedes-Benz E450 have?

The 2026 Mercedes-Benz E450 offers up to 64.6 cubic feet of cargo capacity, depending on trim and seating configuration.

How many trims does the 2026 Mercedes-Benz E450 come in?

The 2026 Mercedes-Benz E450 is available in 1 trim (2 total configurations) across Sedan and Wagon body styles with all wheel drive.

2026 Mercedes-Benz E450

1 trim · 2 configurations · Sedan, Wagon

Starting MSRP

$72,300 – $78,300

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Pricing

How much should you pay for the Mercedes-Benz E450? Select a trim to update purchase and lease estimates.

MSRP by trim

$72,300

Starting MSRP

Purchase information

Based on E 450 4MATIC

Total price (E 450 4MATIC MSRP)

$72,300

Typical monthly

$1,432/mo

Avg. APR

7.00%

60-month loan estimate for good credit (rates as of 2026-07-12). Not a credit offer; actual APR varies by lender, credit, and dealer.

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Compare 2026 Mercedes-Benz E450 trims

E 450 4MATIC
2 configurations
MSRP
$72,300 – $78,300
Fuel economy (city/hwy)
22/31
Horsepower
375 hp
Torque
369 lb-ft
Engine
3L I6 mild hybrid
Seating
5
Drivetrain
AWD
Cargo (cu ft)
12.7
Max towing
—

Compare 2026 Mercedes-Benz E450 trim specifications
Spec	E 450 4MATIC2 configurations
MSRP	$72,300 – $78,300
Fuel economy (city/hwy)	22/31
Horsepower	375 hp
Torque	369 lb-ft
Engine	3L I6 mild hybrid
Seating	5
Drivetrain	AWD
Cargo (cu ft)	12.7
Max towing	—

Specifications shown for each trim’s base configuration; drivetrain, cab, and box options vary within a trim, and MSRP shows the full range. MSRP excludes destination fees, taxes, and dealer-installed options.

Full specifications

Shown for each trim's base configuration. Drivetrain, cab, and box options within a trim can change dimensions, capacities, and fuel economy.

Engine & drivetrain

Engine type: mild hybrid
Fuel type: premium unleaded (required)
Cylinders: I6
Displacement: 3 L
Horsepower: 375 hp
Torque: 369 lb-ft
Transmission: 9-speed shiftable automatic
Drivetrain: all wheel drive

Dimensions

Body type: Sedan
Doors: 4
Seating: 5
Length: 194.9 in
Width: 74 in
Height: 57.9 in
Wheelbase: 116.6 in

Capacity & weight

Cargo capacity: 12.7 cu ft
Max cargo capacity: 12.7 cu ft
Curb weight: 4,376 lbs
Fuel tank: 17.4 gal

Fuel economy & EV

Combined MPG: 25
City MPG: 22
Highway MPG: 31

Full specifications by trim
Spec	Value
Engine & drivetrain
Engine type	mild hybrid
Fuel type	premium unleaded (required)
Cylinders	I6
Displacement	3 L
Horsepower	375 hp
Torque	369 lb-ft
Transmission	9-speed shiftable automatic
Drivetrain	all wheel drive
Dimensions
Body type	Sedan
Doors	4
Seating	5
Length	194.9 in
Width	74 in
Height	57.9 in
Wheelbase	116.6 in
Capacity & weight
Cargo capacity	12.7 cu ft
Max cargo capacity	12.7 cu ft
Curb weight	4,376 lbs
Fuel tank	17.4 gal
Fuel economy & EV
Combined MPG	25
City MPG	22
Highway MPG	31